Main Individual properties of FlexiOss® are as follows:
flexible after soaking (plastic and bendable)
bio-compatible with natural bone tissue
mechanical parameters similar to those of cancellous bone
actively supports bone reconstruction process
absorbs blood and medicine solutions
positively affects bone tissue regeneration process
ionic reactive / bioactive
non-toxic material
can be used for defects of up to 7 cm in length
non-animal material (lowering risk of pathogen transmission and appearance of allergic reactions)
easy to carry and store
What makes FlexiOss® unique
Surgical handiness |
Surgical handiness allows to fit the composite during the operation to the shape of individual bone defects by cutting or bending. |
Can be milled |
In a dry state, FlexiOss® can be milled which enables the personalization of the composite implant. |
Faster ossification |
High specific surface area (due to the high microporosity of granules), high ionic reactivity (adsorption of calcium and phosphate ions from surroundings liquid which allows to increase the rate of mineralization within the implantation site and increase the rate of new bone tissue formation). |
Minimizes the risk of viruses and prions contamination |
Application of carbohydrate polymer to produce FlexiOss® composite minimizes the risk of viruses and prions contamination. Curdlan undergoes gelling, forming the structure of irreversible, collagen-like triple helix – the conformation which is neutral for macrophages and does not evoke the appearance of local inflammation. |
High soaking capacity |
FlexiOss® exhibits high soaking capacity. This simplifies the nutrient supply to the biomaterial within the implantation site and removal of metabolic degradation products, thus increasing the rate of bone tissue regeneration. Before the implantation, it can be soaked in a solution of antibacterial drugs, thus minimizing the risk of perioperative infections and implant rejection. Due to its properties, it can be also soaked in, for example, platelet-rich plasma (PRP) and solution of growth factors (commercial or isolated from patient’s blood). Thus, the biomaterial may resemble (in its properties) very expensive bone-substitutes containing BMP-2-type growth factors. |
Can be easily stored and transported. |
Can be easily stored and transported. |
The exceptional properties of FlexiOss® mentioned above result from its unique composition (hydrogel-like carbohydrate polymer and highly microporous hydroxyapatite ceramics) which does not appear in other bone-substituting biomaterials, neither commercial nor experimental ones.
